Bioinformatics Software (listed in alphabetical order)
Name | Application purpose | Links | Program type | Module name | Server |
---|---|---|---|---|---|
ABySS | NGS, assembly | publication, tutorial | command line tool | ABYSS | gwdu100, HPC |
parallel assembler for short read sequence data | |||||
ALLPATHS-LG | NGS, assembly | homepage, tutorial | command line tool | ALLPATHSLG | gwdu100, HPC |
short read genome assembler | |||||
AMOS | NGS, assembly | publication, tutorial | command line tool | AMOS | gwdu100, HPC |
modular open source whole genome assembler | |||||
AUGUSTUS | gene prediction, genomics | homepage | command line tool | AUGUSTUS | gwdu100, HPC |
gene prediction program for eukaryotes | |||||
BamTools | NGS, sequence alignment | tutorial | command line tool | BAMTOOLS | gwdu100, HPC |
command-line toolkit for for handling genome alignment files | |||||
BBMap | NGS, sequence alignment | homepage, tutorial | command line tool | BBMAP | gwdu100, HPC |
a splice-aware global aligner for DNA and RNA sequencing reads | |||||
BCFtools | NGS, utilities, variants | homepage, tutorial | command line tool | BCFTOOLS | gwdu100, HPC |
utilities for variant calling and manipulating VCFs and BCFs | |||||
bcl2fastq | NGS, utilities | homepage | command line tool | BCL2FASTQ | gwdu100, HPC |
demultiplexes data and converts BCL files generated by Illumina sequencing systems to standard FASTQ file formats | |||||
Beagle | analysis, genomics | homepage | command line tool | BEAGLE | gwdu100, HPC |
software package for analysis of large-scale genetic data sets | |||||
BEAST | phylogenetics | homepage | command line tool | BEAST | gwdu100, HPC |
Software package for phylogenetic analysis with an emphasis on time-scaled trees. | |||||
Beast2 | phylogenetics | homepage | command line tool | BEAST2 | gwdu100, HPC |
Bayesian Evolutionary Analysis by Sampling Trees (rewrite of BEAST) | |||||
bedtools | genomics, utilities | homepage, tutorial | command line tool | BEDTOOLS | Galaxy, gwdu100, HPC |
toolset for genome arithmetic | |||||
BESST | NGS, scaffolding | publication, tutorial | command line tool | BESST | gwdu100, HPC |
scaffolding of large fragmented assemblies | |||||
BinPacker | NGS, assembly | publication | command line tool | BINPACKER | HPC |
packing-based de novo transcriptome assembly from RNA-seq data | |||||
BioPerl | toolkit | homepage | command line tool | BIOPERL | gwdu100, HPC |
open source bioinformatics toolkit for writing bioinformatics scripts | |||||
biotools | utilities | homepage | command line tool | BIOTOOLS | gwdu100, HPC |
Python package of bioinformatics utilities | |||||
Bowtie 1 | NGS, sequence alignment | homepage | command line tool | BOWTIE1 | Galaxy, gwdu100, HPC |
ultrafast, memory-efficient short read aligner | |||||
Bowtie 2 | NGS, sequence alignment | homepage | command line tool | BOWTIE2 | Galaxy, gwdu100, HPC |
ultrafast and memory-efficient tool for aligning sequencing reads to long reference sequences | |||||
Bracken | metagenomics | homepage | command line tool | BRACKEN | gwdu100, HPC |
A highly accurate statistical method that computes the abundance of species in DNA sequences from a metagenomics sample. Braken uses taxonomy labels assigned by Kraken/Kraken2. | |||||
BUSCO | NGS, quality control, special purpose | homepage, publication | command line tool | BUSCO | gwdu100, HPC |
quantitative measures for the assessment of genome assembly, gene set, and transcriptome completeness | |||||
BUSTER | structural biology | homepage, tutorial | command line tool | BUSTER | gwdu100, HPC |
crystallographic structure refinement using Bayesian statistical methods | |||||
Burrows-Wheeler Aligner | NGS, sequence alignment | homepage | command line tool | BWA | Galaxy, gwdu100, HPC |
software package for mapping low-divergent sequences against a large reference genome | |||||
Canu | NGS, assembly, nanopore sequencing | documentation | command line tool | CANU | gwdu100, HPC |
Canu is a fork of the Celera Assembler designed for high-noise single-molecule sequencing (such as the PacBio RSII or Oxford Nanopore MinION). | |||||
CEAS | genomics, special purpose | homepage | command line tool | CEAS | gwdu100, HPC |
Cis-regulatory Element Annotation System for characterization of genome-wide protein-DNA interaction patterns from ChIP | |||||
Celera Assembler | NGS, assembly | homepage | command line tool | CELERA_ASSEMBLER | gwdu100, HPC |
de novo whole-genome shotgun (WGS) DNA sequence assembler | |||||
Cell Ranger | NGS, sequence alignment, single cell analysis | homepage | command line tool | CELL_RANGER | gwdu100, HPC |
A set of analysis pipelines that process Chromium single cell 3' RNA-seq output to align reads, generate gene-cell matrices and perform clustering and gene expression analysis. For viewer software, see Loupe Cell Browser. | |||||
Cicero | NGS, single cell analysis | homepage | command line tool | CICERO | gwdu100, HPC |
Cicero is an R package that provides tools for analyzing single-cell chromatin accessibility experiments. | |||||
Circos | visualization | homepage | command line tool | CIRCOS | gwdu100, HPC |
software package for visualizing data and information in a circular layout | |||||
Clustal W | multiple sequence alignment, sequence alignment | homepage, tutorial | command line tool | CLUSTALW | gwdu100, HPC |
command-line tool for multiple alignment of nucleic acid and protein sequences | |||||
Clustal X | multiple sequence alignment, sequence alignment | homepage, tutorial | graphical user interface | CLUSTALX | gwdu100, HPC |
version of Clustal W with a GUI | |||||
CNVnator | genomics, special purpose | publication, tutorial | command line tool | CNVNATOR | gwdu100, HPC |
a tool for CNV discovery and genotyping from depth-of-coverage by mapped reads | |||||
ctffind | electron microscopy | homepage | command line tool | CTFFIND | gwdu100, HPC |
program for finding CTFs of electron micrographs | |||||
Cufflinks | NGS, analysis, assembly | homepage | command line tool | CUFFLINKS | gwdu100, HPC |
assembles transcripts, estimates their abundances, and tests for differential expression and regulation in RNA-Seq samples | |||||
Cutadapt | NGS, filter/trimming | publication, tutorial | command line tool | CUTADAPT | gwdu100, HPC |
searches for the adapter in all reads and removes it when found | |||||
deepTools | NGS, analysis | homepage | command line tool | DEEPTOOLS | Galaxy, gwdu100, HPC |
command-line tools to process and analyze deep sequencing data | |||||
DELLY2 | analysis, genomics, variants | publication, tutorial | command line tool | DELLY2 | gwdu100, HPC |
structural variant discovery by integrated paired-end and split-read analysis | |||||
DESeq | NGS, analysis | publication, homepage | command line tool | DESEQ | Galaxy, gwdu100, HPC |
differential gene expression of RNA-seq data at the gene level | |||||
DETONATE | NGS, assembly | homepage | command line tool | DETONATE | gwdu100, HPC |
de novo transcriptome RNA-seq assembly | |||||
DEXSeq | NGS, special purpose | publication, homepage | command line tool | DEXSEQ | gwdu100, HPC |
package for finding differential exon usage using RNA-seq exon counts | |||||
DIALS | structural biology | homepage | command line tool | DIALS | HPC |
diffraction integration software for X-ray crystallography | |||||
Entrez Direct | utilities | homepage | command line tool | EDIRECT | gwdu100, HPC |
Entrez Direct (EDirect) provides access to the NCBI's suite of interconnected databases (publication, sequence, structure, gene, variation, expression, etc.) from a UNIX terminal window. | |||||
EMBOSS | analysis, toolkit | homepage, tutorial | command line tool | EMBOSS | Galaxy, gwdu100, HPC |
analysis package for molecular biology (all programs are listed by command 'wossname', a detailed program description is displayed by 'tfm program_name') | |||||
exomePeak | NGS, analysis | publication, homepage | command line tool | EXOMEPEAK | gwdu100, HPC |
exome-based analysis for RNA epigenome sequencing data | |||||
Exonerate | sequence alignment | homepage | command line tool | EXONERATE | gwdu100, HPC |
sequence alignment tool for pairwise sequence comparison | |||||
eXpress | NGS, special purpose | homepage | command line tool | EXPRESS | gwdu100, HPC |
streaming fragment assignment and quantification for high-throughput sequencing | |||||
FASTA | sequence alignment | homepage | command line tool | FASTA | gwdu100, HPC |
sequence comparison | |||||
FastQC | NGS, quality control | homepage | command line tool | FASTQC | Galaxy, gwdu100, HPC |
quality control tool for high throughput sequence data | |||||
fastStructure | NGS, phylogenetics | homepage, publication | command line tool | FASTSTRUCTURE | gwdu100, HPC |
A variational framework for inferring population structure from SNP genotype data. | |||||
FASTX | NGS, toolkit | homepage | command line tool | FASTX | gwdu100, HPC |
collection of command line tools for Short-Reads FASTA/FASTQ files preprocessing | |||||
Filtlong | NGS, filter/trimming | homepage | command line tool | FILTLONG | gwdu100, HPC |
Filtlong is a tool for filtering long reads by quality. | |||||
FitHiChIP | Hi-C, NGS | homepage, publication | command line tool | FITHICHIP | gwdu100, HPC |
Statistically Significant loops from HiChIP data | |||||
Flappie | NGS, nanopore sequencing | homepage | command line tool | FLAPPIE | gwdu100, HPC |
Flip-flop basecaller for Oxford Nanopore reads. | |||||
Flye | NGS, assembly, nanopore sequencing | homepage | command line tool | FLYE | gwdu100, HPC |
Flye is a de novo assembler for single molecule sequencing reads. | |||||
freebayes | SNP, variants | homepage | command line tool | FREEBAYES | gwdu100, HPC |
Bayesian haplotype-based genetic polymorphism discovery and genotyping. | |||||
GapFiller | NGS, scaffolding | publication | command line tool | GAPFILLER | gwdu100, HPC |
stand-alone program for closing gaps within pre-assembled scaffolds | |||||
GATK | NGS, variants | homepage | command line tool | GATK | gwdu100, HPC |
toolkit for variant discovery in high-throughput sequencing data | |||||
Geneious | NGS, analysis, assembly, molecular biology, sequence alignment, special purpose, visualization | homepage | graphical user interface | GENEIOUS | gwdu100 |
a powerful and comprehensive suite of molecular biology and NGS analysis tools with very good visualization | |||||
GenomeTools | analysis, genomics | homepage | command line tool | GENOMETOOLS | gwdu100, HPC |
bioinformatics tools for genome analysis | |||||
GMAP/GSNAP | sequence alignment | homepage | command line tool | GMAP | gwdu100, HPC |
GMAP: Genomic Mapping and Alignment Program for mRNA and EST Sequences. GSNAP: Genomic Short-read Nucleotide Alignment Program | |||||
Gromacs | structural biology | homepage | command line tool | GROMACS | HPC |
a versatile package to perform molecular dynamics, i.e. simulate the Newtonian equations of motion for systems with hundreds to millions of particles | |||||
Guppy | NGS, nanopore sequencing | homepage | command line tool | GUPPY | gwdu100, HPC |
Accelerated basecaller for Oxford Nanopore Sequencing | |||||
Hail | NGS, analysis, annotation, quality control, toolkit, visualization | homepage | command line tool | HAIL | HPC |
Hail is an open-source, scalable framework for exploring and analyzing genomic data. | |||||
HMMER | sequence alignment, special purpose | homepage | command line tool | HMMER | gwdu100, HPC |
biosequence analysis using profile hidden Markov models | |||||
HiC-Pro | Hi-C, NGS, visualization | documentation, publication | command line tool | HIC-PRO | gwdu100, HPC |
HiC-Pro: An optimized and flexible pipeline for Hi-C data processing | |||||
hichipper | Hi-C, NGS, quality control | homepage, documentation | command line tool | HICHIPPER | gwdu100, HPC |
hichipper is a command-line toolkit that performs restriction fragment bias-aware preprocessing of HiChIP data. | |||||
HISAT2 | NGS, sequence alignment | homepage | command line tool | HISAT2 | Galaxy, gwdu100, HPC |
A fast and sensitive alignment program for mapping next-generation sequencing reads (both DNA and RNA) to a population of human genomes (as well as to a single reference genome). | |||||
HOMER | NGS, analysis, toolkit | homepage | command line tool | HOMER | gwdu100, HPC |
suite of tools for Motif Discovery and next generation sequencing analysis | |||||
HTSeq | NGS, utilities | publication, homepage | command line tool | HTSEQ | Galaxy, gwdu100, HPC |
Python package that provides infrastructure to process data from high-throughput sequencing assays | |||||
IDBA | NGS, assembly | homepage | command line tool | IDBA | gwdu100, HPC |
de novo assembler for short reads sequencing data with highly uneven sequencing depths | |||||
Integrative Genomics Viewer | genome browser, genomics, visualization | homepage, publication | graphical user interface | IGV | gwdu100, HPC |
high-performance visualization tool for genomic datasets | |||||
iMOSFLM | structural biology | homepage | graphical user interface | iMOSFLM | HPC |
a program for integrating single crystal diffraction data from area detectors | |||||
InterProScan | analysis, protein, special purpose | homepage, publication | command line tool | INTERPROSCAN | gwdu100, HPC |
protein sequence search | |||||
ipyrad | NGS, RADseq, analysis, assembly | documentation | command line tool | IPYRAD | gwdu100, HPC |
interactive assembly and analysis of RADseq data sets | |||||
Jellyfish | utilities | homepage, tutorial | command line tool | JELLYFISH | gwdu100, HPC |
A tool for fast, memory-efficient counting of k-mers in DNA | |||||
JMP Genomics | NGS, genomics, visualization | homepage | graphical user interface | GWD-WinTSBio | |
advanced genomic data analysis software with very good visualization (part of the SAS-JMP-bundle) | |||||
kallisto | NGS, analysis | homepage, publication | command line tool | KALLISTO | gwdu100, HPC |
program for quantifying abundances of transcripts from RNA-Seq data | |||||
Katuali | NGS, analysis, nanopore sequencing | homepage, documentation | command line tool | KATUALI | gwdu100, HPC |
Katuali is a flexible consensus pipeline implemented in Snakemake to basecall, assemble, and polish Oxford Nanopore Technologies' sequencing data. | |||||
KisSplice | NGS, assembly | homepage | command line tool | KISSPLICE | gwdu100, HPC |
local transcriptome assembler for SNPs, indels and AS events | |||||
KNIME | utilities | homepage | graphical user interface | KNIME | gwdu100 |
more than 1500 modules, hundreds of ready-to-run examples, community contributions, and tool integrations | |||||
Kraken2 | classification, metagenomics | homepage | command line tool | KRAKEN2 | gwdu100, HPC |
A taxonomic classification system using exact k-mer matches to achieve high accuracy and fast classification speeds. The assisting tool Bracken is available in a separate module. | |||||
kSNP | SNP, phylogenetics, variants | homepage | command line tool | KSNP | gwdu100, HPC |
kSNP identifies the pan-genome SNPs in a set of genome sequences, and estimates phylogenetic trees based upon those SNPs. | |||||
LoRDEC | NGS, quality control | homepage | command line tool | LORDEC | gwdu100, HPC |
LoRDEC is a program to correct sequencing errors in long reads from 3rd generation sequencing with high error rate, and is especially intended for PacBio reads. | |||||
Loupe Cell Browser | NGS, analysis, visualization | homepage | graphical user interface | GWD-WinTSBio | |
A desktop application for Windows and MacOS that allows you to quickly and easily visualize and analyze 10x Chromium Single Cell 5' and 3' gene expression data. | |||||
MACS2 | ChIP-Seq, NGS, analysis | homepage | command line tool | MACS2 | Galaxy, gwdu100, HPC |
Model-based Analysis of ChIP-Seq data for identifying transcript factor binding sites | |||||
MAFFT | multiple sequence alignment, sequence alignment | homepage, publication | command line tool | MAFFT | gwdu100, HPC |
multiple alignment program for amino acid or nucleotide sequences | |||||
MAKER | annotation, genomics | homepage, publication | command line tool | MAKER | gwdu100, HPC |
genome annotation pipeline | |||||
MarkerMiner | NGS, analysis, phylogenetics | homepage, publication | command line tool | MARKERMINER | gwdu100, HPC |
fully automated workflow and application for discovery of SCN loci in angiosperms | |||||
MARVEL | NGS, assembly, nanopore sequencing | homepage | command line tool | MARVEL | gwdu100, HPC |
MARVEL consists of a set of tools that facilitate the overlapping, patching, correction and assembly of noisy (not so noisy ones as well) long reads. | |||||
Mauve | multiple sequence alignment, sequence alignment | homepage, publication | graphical user interface | MAUVE | Galaxy, gwdu100, HPC |
Mauve is a system for constructing multiple genome alignments in the presence of large-scale evolutionary events such as rearrangement and inversion. | |||||
Medaka | NGS, nanopore sequencing | homepage, documentation | command line tool | MEDAKA | gwdu100, HPC |
Medaka is a tool to create a consensus sequence from nanopore sequencing data. | |||||
MEME | analysis, special purpose, toolkit | homepage | command line tool | MEME | Galaxy, gwdu100, HPC |
supports motif-based analysis of DNA, RNA and protein sequences | |||||
Miniasm | NGS, assembly, nanopore sequencing | homepage | command line tool | MINIASM | gwdu100, HPC |
Ultrafast de novo assembly for long noisy reads (though having no consensus step) | |||||
Minimap2 | NGS, nanopore sequencing, sequence alignment | homepage, publication, manual | command line tool | MINIMAP2 | gwdu100, HPC |
A versatile pairwise aligner for genomic and spliced nucleotide sequences | |||||
MIRA | NGS, assembly | homepage | command line tool | MIRA | gwdu100, HPC |
a multi-pass DNA sequence data assembler/mapper for whole genome and EST/RNA-seq projects | |||||
miRDeep2 | NGS, analysis, special purpose | documentation, publication, tutorial | command line tool | MIRDEEP2 | gwdu100, HPC |
A tool for discovering known and novel miRNAs from small RNA sequencing data. | |||||
miRExpress | NGS, analysis, special purpose | homepage, publication | command line tool | MIREXPRESS | gwdu100, HPC |
tool to analyze high-throughput sequencing data for profiling microRNA expression | |||||
Miropeats | visualization | homepage | command line tool | MIROPEATS | gwdu100, HPC |
Miropeats discovers regions of sequence similarity amongst any set of DNA sequences and presents this similarity information graphically. | |||||
mirPRo | NGS, analysis, special purpose | homepage, publication | command line tool | MIRPRO | gwdu100, HPC |
a novel standalone program for differential expression and variation analysis of miRNAs | |||||
Monocle3 | single cell analysis | homepage | command line tool | MONOCLE3 | gwdu100, HPC |
Monocle 3 is an analysis toolkit for single-cell RNA-Seq experiments. | |||||
mothur | microbial ecology | homepage | command line tool | MOTHUR | gwdu100, HPC |
open-source expandable software for the bioinformatic needs of microbial ecology | |||||
MOTHUR-GUI | microbial ecology | homepage | graphical user interface | MOTHUR-GUI | gwdu100, HPC |
Gui version of mothur | |||||
MrBayes | phylogenetics | homepage | command line tool | MRBAYES | gwdu100, HPC |
program for Bayesian inference and model choice across a wide range of phylogenetic and evolutionary models | |||||
MUMmer | sequence alignment | homepage | command line tool | MUMMER | gwdu100, HPC |
a system for rapidly aligning entire genomes | |||||
MUSCLE | multiple sequence alignment | homepage, publication | command line tool | MUSCLE | gwdu100, HPC |
multiple sequence alignment | |||||
Nanofilt | NGS, filter/trimming, nanopore sequencing | homepage, publication | command line tool | NANOFILT | gwdu100, HPC |
Filtering and trimming of long read sequencing data | |||||
Nanopolish | NGS, assembly, nanopore sequencing | manual | command line tool | NANOPOLISH | gwdu100, HPC |
Software package for signal-level analysis of Oxford Nanopore sequencing data | |||||
NanoStat | NGS, nanopore sequencing | homepage, publication | command line tool | NANOSTAT | gwdu100, HPC |
Create statistic summary of an Oxford Nanopore read dataset | |||||
NCBI-BLAST | classification, sequence alignment | homepage | command line tool | NCBI-BLAST | Galaxy, gwdu100, HPC |
basic local alignment search tool | |||||
NCBI-TOOLS | NGS, toolkit | homepage | command line tool | NCBI-TOOLS | gwdu100, HPC |
more than 700 tools, e.g. for downloading custom data sets | |||||
ngs.plot | NGS, visualization | publication | command line tool | NGSPLOT | gwdu100, HPC |
a standalone program to visualize enrichment patterns of DNA-interacting proteins at functionally important regions based on NGS data. | |||||
Oases | NGS, assembly | homepage, publication | command line tool | OASES | gwdu100, HPC |
de novo transciptome assembler for very short reads | |||||
PartitionFinder | phylogenetics | homepage | command line tool | PARTITIONFINDER | gwdu100, HPC |
select best-fit partitioning schemes and models of molecular evolution for phylogenetic analyses | |||||
Pauvre | NGS, genome browser, nanopore sequencing | homepage | command line tool | PAUVRE | HPC |
QC and genome browser plotting Oxford Nanopore and PacBio long reads | |||||
PGURE-SVT | microscopy | homepage, publication | command line tool | PGURESVT | gwdu100, HPC |
algorithm for denoising time-resolved microscopy image sequences | |||||
phASER | special purpose | homepage, publication | command line tool | PHASER | gwdu100, HPC |
phasing and Allele Specific Expression from RNA-seq | |||||
PHYLIP | phylogenetics | homepage | command line tool | PHYLIP | gwdu100, HPC |
PHYLogeny Inference Package: programs for inferring phylogenies | |||||
PhyML | phylogenetics | homepage | command line tool | PHYML | Galaxy, gwdu100, HPC |
Phylogenetic estimation using (Maximum) Likelihood | |||||
Picard | NGS | homepage | command line tool | PICARD | Galaxy, gwdu100, HPC |
set of command line tools for manipulating high-throughput sequencing (HTS) data and formats such as SAM/BAM/CRAM and VCF | |||||
Pilon | NGS, assembly, variants | homepage | command line tool | PILON | gwdu100, HPC |
Pilon is an automated genome assembly improvement and variant detection tool. | |||||
Platanus | NGS, assembly | homepage, publication | command line tool | PLATANUS | gwdu100, HPC |
PLATform for Assembling NUcleotide Sequences is a novel de novo sequence assembler that can reconstruct genomic sequences of highly heterozygous diploids from massively parallel shotgun sequencing data | |||||
PLINK | analysis, genomics, toolkit | homepage | command line tool | PLINK | gwdu100, HPC |
whole genome association analysis toolset, designed to perform a range of basic, large-scale analyses in a computationally efficient manner | |||||
POPBAM | NGS, phylogenetics | publication | command line tool | POPBAM | gwdu100, HPC |
tools for evolutionary analysis of short read sequence alignments | |||||
Pomoxis | NGS, analysis, nanopore sequencing | documentation | command line tool | POMOXIS | gwdu100, HPC |
Pomoxis comprises a set of basic bioinformatic tools tailored to nanopore sequencing. | |||||
Porechop | NGS, filter/trimming, nanopore sequencing | homepage | command line tool | PORECHOP | HPC |
adapter trimmer for Oxford Nanopore reads | |||||
poretools | NGS, nanopore sequencing, toolkit | homepage | command line tool | PORETOOLS | gwdu100, HPC |
toolkit for working with nanopore sequencing data from Oxford Nanopore | |||||
PROFphd | protein, structural biology | homepage | command line tool | PROFPHD | gwdu100, HPC |
Predicts protein secondary structure using a system of neural networks | |||||
Proteome Discoverer | protein | homepage | graphical user interface | GWD-WinTSBio | |
only usable as viewer on our server | |||||
pyRAD | NGS, RADseq, assembly, phylogenetics | publication | command line tool | PYRAD | gwdu100, HPC |
assembly of de novo RADseq loci for phylogenetic analyses | |||||
QUAST | NGS, quality control | homepage, manual | command line tool | QUAST | gwdu100, HPC |
QUAST stands for QUality ASsessment Tool. The tool evaluates genome assemblies by computing various metrics. | |||||
Racon | NGS, assembly | publication, tutorial | command line tool | RACON | gwdu100, HPC |
ultrafast consensus module for raw de novo genome assembly of long uncorrected reads | |||||
RAxML | phylogenetics | homepage | command line tool | RAXML | gwdu100, HPC |
Randomized Axelerated Maximum Likelihood: tool for maximum-likelihood based phylogenetic inference | |||||
RAxML Next Generation | phylogenetics | documentation, publication | command line tool | RAXML-NG | gwdu100, HPC |
A phylogenetic tree inference tool which uses maximum-likelihood (ML) optimality criterion. | |||||
RECON | genomics, special purpose | homepage, publication | command line tool | RECON | gwdu100, HPC |
program for prediction of nucleosome formation potential | |||||
RELION | electron microscopy | tutorial | graphical user interface | RELION | gwdu100, HPC |
REgularised LIkelihood OptimisatioN: a program for an empirical Bayesian approach to refinement of (multiple) 3D reconstructions or 2D class averages in electron cryo-microscopy | |||||
RepeatMasker | genomics, special purpose | homepage | command line tool | REPEATMASKER | gwdu100, HPC |
program that screens DNA sequences for interspersed repeats and low complexity DNA sequences | |||||
Rgui | statistics | homepage | graphical user interface | GWD-WinTSBio | |
graphical user interface for R | |||||
Rosetta | protein, structural biology | homepage | command line tool | ROSETTA | HPC |
software suite including algorithms for computational modeling and analysis of protein structures | |||||
RSEM | NGS, analysis | publication | command line tool | RSEM | gwdu100, HPC |
accurate transcript quantification from RNA-Seq data with or without a reference genome | |||||
RSeQC | NGS, quality control | homepage | command line tool | RSEQC | gwdu100, HPC |
a package that provides a number of useful modules that can comprehensively evaluate high throughput sequence data especially RNA-seq data | |||||
Rstudio | statistics | homepage | graphical user interface | GWD-WinTSBio | |
A free and open-source environment for R, a programming language for statistical computing. Also available as RStudio-Server. | |||||
Salmon | NGS, analysis | homepage | command line tool | SALMON | gwdu100, HPC |
A tool for quantifying the expression of transcripts using RNA-seq data. | |||||
Samtools | NGS, sequence alignment, utilities | homepage | command line tool | SAMTOOLS | Galaxy, gwdu100, HPC |
various utilities for manipulating alignments in the SAM format, including sorting, merging, indexing and generating alignments in a per-position format | |||||
Scallop | NGS, assembly | homepage, publication | command line tool | SCALLOP | HPC |
Scallop is a reference-based transcriptome assembler for RNA-seq. | |||||
Scrappie | NGS, nanopore sequencing | homepage | command line tool | SCRAPPIE | HPC |
Basecaller for Oxford Nanopore Sequencing | |||||
Shasta | NGS, nanopore sequencing | documentation | command line tool | SHASTA | gwdu100, HPC |
De novo assembly from Oxford Nanopore reads. | |||||
SignalP | protein, special purpose | homepage, publication | command line tool | SIGNALP | gwdu100, HPC |
prediction of presence and location of signal peptide cleavage sites in amino acid sequences | |||||
simRRLs | phylogenetics, special purpose | homepage | command line tool | SIMRRLS | gwdu100, HPC |
simulation of raw restriction-site associated DNA fastq files for testing assembly methods on raw data | |||||
SINA | multiple sequence alignment, sequence alignment | homepage, publication | command line tool | SINA | gwdu100, HPC |
tool for aligning sequences with an existing multiple sequence alignment (MSA) at high accuracy | |||||
SMARTdenovo | NGS, assembly, nanopore sequencing | homepage | command line tool | SMARTDENOVO | gwdu100, HPC |
Ultra-fast de novo assembler using long noisy reads. | |||||
SNAP | gene prediction, genomics | homepage | command line tool | SNAP | gwdu100, HPC |
Semi-HMM-based Nucleic Acid Parser: a gene prediction tool | |||||
Snippy | NGS, SNP, variants | homepage | command line tool | SNIPPY | gwdu100, HPC |
Rapid haploid variant calling and core genome alignment | |||||
SnpEff | annotation, variants | homepage | command line tool | SNPEFF | Galaxy, gwdu100, HPC |
Genomic variant annotations and functional effect prediction toolbox. | |||||
SNPiR | NGS, SNP, analysis, variants | publication | command line tool | SNPIR-TOOL | gwdu100, HPC |
a suite of tools for reliable identification of genomic variants using RNA-seq data | |||||
SOAPaligner | NGS, sequence alignment | homepage | command line tool | SOAP2-ALIGNER | gwdu100, HPC |
alignment tool | |||||
SOAPdenovo | NGS, assembly | homepage | command line tool | SOAP2-DENOVO | gwdu100, HPC |
de novo short reads assembler | |||||
SOAPdenovo-Trans | NGS, assembly | homepage, publication | command line tool | SOAP-DENOVO-TRANS | gwdu100, HPC |
A de novo transcriptome assembler designed specifically for RNA-Seq. | |||||
SortMeRNA | NGS, filter/trimming, special purpose | homepage | command line tool | SORTMERNA | gwdu100, HPC |
a program tool for filtering, mapping and OTU-picking NGS reads in metatranscriptomic and metagenomic data | |||||
SPAdes | NGS, assembly | homepage, manual | command line tool | SPADES | gwdu100, HPC |
An assembly toolkit containing various assembly pipelines. | |||||
SRA-Toolkit | NGS, utilities | publication | command line tool | SRATOOLKIT | Galaxy, gwdu100, HPC |
toolkit to convert .sra files into other formats | |||||
SRST2 | special purpose | homepage | command line tool | SRST2 | gwdu100, HPC |
Short Read Sequence Typing for Bacterial Pathogens | |||||
SSPACE-LongRead | NGS, scaffolding | homepage, publication | command line tool | SSPACE-LONGREAD | gwdu100, HPC |
a program for scaffolding longreads (e.g. PacBio RS reads) | |||||
SSPACE-Standard | NGS, scaffolding | homepage, publication | command line tool | SSPACE-STANDARD | gwdu100, HPC |
a program for scaffolding pre-assembled contigs using NGS paired-read data | |||||
Stacks | NGS, special purpose | homepage, publication | command line tool | STACKS | gwdu100, HPC |
software pipeline for building loci from short-read sequences | |||||
Staden Package | NGS, analysis, assembly | homepage | graphical user interface | STADEN | gwdu100, HPC |
tools for DNA sequence assembly, editing and sequence analysis | |||||
STAR | NGS, sequence alignment | homepage | graphical user interface | STAR | Galaxy, gwdu100, HPC |
Spliced Transcript Alignment to a Reference: fast RNA-seq read mapper | |||||
Structure | phylogenetics | homepage | graphical user interface | STRUCTURE | gwdu100, HPC |
A software package for using multi-locus genotype data to investigate population structure. | |||||
Subread | NGS, SNP, counting, sequence alignment | homepage | command line tool | SUBREAD | Galaxy, gwdu100, HPC |
High-performance read alignment, quantification and mutation discovery. The package contains the programs Subread, Subjunc, featureCounts, Sublong and exactSNP. | |||||
SVDetect | NGS, variants | homepage, manual | command line tool | SVDETECT | gwdu100, HPC |
SVDetect is a application for the isolation and the type prediction of intra- and inter-chromosomal rearrangements from paired-end/mate-pair sequencing data. | |||||
Tabix | genomics, special purpose | homepage, publication | command line tool | TABIX | gwdu100, HPC |
tool for fast retrieval of sequence features from generic TAB-delimited files | |||||
Tandem Repeats Finder | genomics, special purpose | homepage | command line tool | TANDEMREPEATSFINDER | gwdu100, HPC |
a program to locate and display tandem repeats in DNA sequences | |||||
T-Coffee | multiple sequence alignment, sequence alignment | homepage | command line tool | TCOFFEE | gwdu100, HPC |
a multiple sequence alignment program. Its main characteristic is that it will allow you to combine results obtained with several alignment methods | |||||
Tomahawk | special purpose | homepage | command line tool | TOMAHAWK | gwdu100, HPC |
Fast calculations of linkage-disequilibrium in large-scale human cohorts | |||||
TopHat | NGS, sequence alignment | homepage | command line tool | TOPHAT | Galaxy, gwdu100, HPC |
fast splice junction mapper for RNA-Seq reads that aligns RNA-Seq reads to mammalian-sized genomes using Bowtie | |||||
Trans-ABySS | NGS, assembly | homepage, publication | command line tool | TRANSABYSS | HPC |
de novo assemly of RNA-Seq data | |||||
Transrate | NGS, assembly, quality control | homepage | command line tool | TRANSRATE | gwdu100 |
software for de-novo transcriptome assembly quality analysis | |||||
Trim Galore! | NGS, filter/trimming, quality control | homepage | command line tool | TRIMGALORE | gwdu100, HPC |
wrapper tool around Cutadapt and FastGC to consistently apply quality and adapter trimming to FastQ files | |||||
Trimmomatic | NGS, filter/trimming | homepage | command line tool | TRIMMOMATIC | Galaxy, gwdu100, HPC |
flexible trimmer for Illumina NGS data | |||||
TRINITY | NGS, assembly | homepage, publication | command line tool | TRINITY | Galaxy, gwdu100, HPC |
de novo reconstruction of transcriptomes from RNA-Seq data | |||||
tRNAscan_SE | genomics, special purpose | homepage, publication | command line tool | TRNASCAN-SE | gwdu100, HPC |
a program for improved detection of transfer RNA genes in genomic sequence | |||||
UCSC | genome browser, genomics | homepage | command line tool | UCSC | gwdu100, HPC |
genome browser | |||||
Velvet | NGS, assembly | homepage | command line tool | VELVET | gwdu100, HPC |
sequence assembler for very short reads | |||||
VEP | SNP, variants | homepage | command line tool | VEP | gwdu100, HPC |
Variant Effect Predictor predicts the functional effects of genomic variants. | |||||
Vienna RNA package | structural biology | homepage | command line tool | VIENNA-RNA | gwdu100, HPC |
C code library and several stand-alone programs for the prediction and comparison of RNA secondary structures | |||||
Vlion | electron microscopy | homepage, tutorial | graphical user interface | VLION | HPC |
A slightly vectorized (AVX & SSE instructions) version of the original RELION 1.4 code. | |||||
wtdbg2 | NGS, assembly, nanopore sequencing, sequence alignment | homepage | command line tool | WTDBG2 | gwdu100, HPC |
A de novo sequence assembler for long noisy reads produced by PacBio or Oxford Nanopore Technologies. |
last modified: 14.05.2020 - 11:04